Dengue in Siddha: Siddha system of Medicine describes all types of pyrexia under a heading Suram. It includes the vector borne diseases like malaria, dengue. Siddha correlates dengue to Pitha Suram. Siddha literature, ‘Agastiyar Sura Nool 300’ mentions that the ‘Pitha suram’ can cause bleeding and so we can correlate it to haemorrhage in dengue fever. The symptoms described by the above mentioned text can also be correlated to those given in the definition of Dengue Fever. For prevention of dengue in Siddha System: Nilavembu kudineer - 60 ml daily in the morning for adults and 30 ml for children throughout the dengue season. For treatment of dengue in Siddha System: Nilavembu Kudineer – 60 ml once daily in the morning for adults and 30 ml for children till cure. For the management of dengue haemorrhagic fever: 10-20 drops of Adathodai (Justicia adathoda) leaf juice mixed with equal quantity of honey may be given for Dengue haemorrhagic fever. In dengue haemorrhagic fever it is better to prescribe drugs which are styptics and which increases the platelet count. Along with the above said prescription the following medicines can be added: For management of fever Nilavembu kudineer, Pittasura kudineer, Bramhananda Bairavam Tablet. For prevention of haemorrhagic symptoms Imbural vatakam Padiga poongavi Chenduram Kavikkal Chooranam General health improvement Nellikkai lehyam – 5 Gm BID Triphala chooranam tablet – 2 BID Amukkara chooranam tablet- 2 For prevention of recurrence: Regular use of Nilavembu Kudineer and Adathodai Kudineer will help much. Haemorrhage - Papaya leaf juice 5 ml Daily increases platelet production. Vector control: Application of Karpoorathy Thylam Neem leaves Fumigation Usage of Poonkarpooram instead of Mosquito repellent mats Closed Storage of Water. Spraying of Mosquitocidal spray in Water logged areas. Evidence based Siddha Medicine: Compound / Single formulation (evidence based) 1. Nilavembu kudineer a) Antipyretic, Analgesic, Anti-dengue activity proved. The methanol extracts of Andrographics paniculata and Memorida charantia possess the ability of inhibiting the activity of DENV-1 in in vitro assays (Anna PK ling et al, 2012). b) Ethanolic extract of Nilavembu kudineer chooranam (EENKC) possesses antipyretic, anti-inflammatory and analgesic activity which supports Nilavembu kudineer chooranam efficacy in chikungunya fever. (Anbarasu, 2011). 2. Adathodai kudineer (can also be used as larvicidal in prevention of vectors) All the tested fractions have been proved to have strong larvicidal activity (doses from 100 to 250 ppm) against C. Quinque fasciatus and A. aegypti in Methanolic extracts of A.vasica. 3. Veppilai chooranam (Herbal powder) The effect of Azadirachta indica leaf extract and the pure compound - Azadirachtin on the replication of Dengue virus type-2 has also been reported (Parida et al , 2002) Compound / Single formulation (evidence based) 1. Amukkara chooranam Ashwagandha prevents myelosuppression in mice treated with all three immunosuppressive drugs tested. A significant increase in hemoglobin concentration (P < 0.01), red blood cell count (P < 0.01), white blood cell count (P < 0.05), platelet count (P < 0.01), and body weight (P < 0.05) was observed in Ashwagandha-treated mice as compared with untreated (control) mice. We also report an immune stimulatory activity: treatment with Ashwagandha was accompanied by significant increases in hemolytic antibody responses towards human erythrocytes (Ziauddin et al,1996) 2. Amman Pacharisi Karkam The researchers subjected Euphorbia hirta leaves to decoction, a method of extraction performed through boiling. Tawa-tawa’s platelet-increasing activity was tested on laboratory experimental rats, specifically Sprague-Dawley. According to Lopez, results of the study showed that the tawa-tawa extract was effective in increasing the platelet count of rats without notable effects in red blood cell and white blood cell counts. The group also concluded that the platelet increasing property of tawa-tawa works through the stimulation of platelet production in the bone marrow (Lopez et al 2011) Conclusion: The value of any medical system is recognised by the public when they are effectively utilized during the epidemic out breaks.
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